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 Irritation \Ir`ri*ta"tion\, n. [L. irritatio: cf. F.
   irritation.]
   [1913 Webster]
   1. The act of irritating, or exciting, or the state of being
      irritated; excitement; stimulation, usually of an undue
      and uncomfortable kind; especially, excitement of anger or
      passion; provocation; annoyance; anger.
      [1913 Webster]

            The whole body of the arts and sciences composes one
            vast machinery for the irritation and development of
            the human intellect.                  --De Quincey.
      [1913 Webster]

   2. (Physiol.) The act of exciting, or the condition of being
      excited to action, by stimulation; -- as, the condition of
      an organ of sense, when its nerve is affected by some
      external body; esp., the act of exciting muscle fibers to
      contraction, by artificial stimulation; as, the irritation
      of a motor nerve by electricity; also, the condition of a
      muscle and nerve, under such stimulation.
      [1913 Webster]

   3. (Med.) A condition of morbid excitability or
      oversensitiveness of an organ or part of the body; a state
      in which the application of ordinary stimuli produces pain
      or excessive or vitiated action.
      [1913 Webster]